I think the game will be inside of 10 points going into the 4th quarter unless there is a catastrophic injury to one of the quarterbacks, early in the contest... I've predicted Clemson to win, but I'll be cheering my ass off for my Irish. My thought is that Clemson will control the game early, Ian Book will stark relatively slow, as he tends to, then Notre Dame will slowly climb back into the game, culminating in a 4th quarter than could go in either direction.
I'm not going to predict a score, but that's generally how I feel the cadence of the game will workout.