Louisville was picked to finish fourth in the 15-team ACC this year (behind Clemson, Notre Dame and North Carolina), but has started 0-3 in the league. Turnovers, continued woes on defense and maybe even a "sophomore jinx" have all been factors.
https://notredame.rivals.com/news/notre-dame-louisville-the-second-time-around
https://notredame.rivals.com/news/notre-dame-louisville-the-second-time-around