Ed Marinaro and Calvin Hill both had successful NFL careers. Calvin Hill was probably more athletic, but Marinaro was a very strong and tough inside runner. And of course Marinaro had a second career as an actor, most notably with Hill Street Blues.
I grew up as a Bears fan, so I remember another Yale graduate, Gary Fencik, who had a nice run with the Bears. Fencik played receiver at Yale, but was thought to be too slow to play that position in the NFL, so he was converted to safety. He was about to give up on the NFL and start his career in the investment banking business when he caught on with the Bears. Fencik and fellow safety Doug Plank came to be known as the "The Hit Men," and were part of the great 1985 Bears defense. Funny the twists and turns that life can take.